Science

The science reflects quite well the traditional use of purslane, and Portusana® captures the essence of the plant, in a safe, studied, efficient extract. The beneficial effects of Portusana® are the result of the synergistic interplay between the constituents in the plant and cannot be attributed to one single substance.

To assess the efficacy and safety Frutarom´s unique purslane herbal extract, in humans, an open, uncontrolled pilot study was performed on participants with elevated blood glucose not taking blood glucose modulating medication. The supplementation of oral doses equivalent to 180 mg/d Portusana® for five weeks was well tolerated and results demonstrated a progressive improvement of blood glucose levels over time1 . Encouraged by this promising finding, a clinical trial was carried out to confirm these results. In a randomized, double-blind, placebo-controlled study, 63 patients with type 2 diabetes received 60 mg of purslane extract three times daily or a placebo daily for 12 weeks.2

Already after six weeks HbA1c (glycated hemoglobin), a marker for long-term blood glucose control, had improved in almost 80% of patients. After 12 weeks the purslane extract significantly reduced HbA1c from average 7.38% to 6.53% outperforming placebo by 44% ( ≤ 6.5 is recommended by the American College of Endocrinology and indicates good glucose control).

PORTUSANA

No safety or tolerance issues were reported. Based on the findings of these two studies, it may be concluded that Frutarom´s purslane herb extract not only reduces blood glucose levels but also improves long-term glucose control and thus safely assists in blood glucose regulation.

Frutarom continues to fund research to further support the clinical efficacy of Portusana®.

Please contact us for study summaries and more information to Portusana®.

  1. Proprietary data by Frutarom, study summary (Blood Glucose Concentration)
  2. Proprietary data by Frutarom, study summary (Efficacy & Safety)